| Active substance |
Isotretinoin |
| Also known as |
13-cis-Retinoic acid |
| Blood pressure |
No direct effect |
| Chemical name |
(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid |
| Dosage (medical) |
Typically, 0.5 to 1 mg per kg of body weight per day |
| Dosage (sports) |
Not applicable |
| Effects |
Reduces severe acne, decreases sebum production, promotes skin renewal |
| Formula |
C20H28O2 |
| Half-life |
10-20 hours |
| Hepatotoxicity |
Possible, liver function tests are recommended |
| Lab Test |
Liver function tests, lipid profile, pregnancy test |
| Main action |
Reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly |
| Side effects |
Dry skin, itching, dry nose, nosebleeds, cracks in the corners of the mouth, dry mouth, dry lips, cracking or peeling skin, inflammation of the whites of the eyes, tiredness |
| Storage conditions |
Store at controlled room temperature, 15-30В°C (59-86В°F) |
| Substance class |
Retinoid |
| Trade name |
Accutane, Roaccutane, and others |
| Use in sports |
None, not used for performance enhancement |
| Water Retention |
None |
| Manufacturer |
GSK |
| Packing |
30 gr. Tube |