| Active substance |
Isotretinoine |
| Also known as |
13-cis-Retinoic acid |
| Blood pressure |
No significant effect |
| Chemical name |
(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid |
| Dosage (medical) |
Typically 0.5 to 1 mg per kg of body weight per day, taken in two divided doses |
| Dosage (sports) |
Not applicable |
| Effects |
Reduces acne, decreases sebum production, promotes skin renewal |
| Formula |
C20H28O2 |
| Half-life |
10-20 hours |
| Hepatotoxicity |
Moderate, requires periodic liver function tests |
| Lab Test |
Liver function tests, lipid profiles, pregnancy tests |
| Main action |
Reduces sebum production, corrects abnormal keratinization, has anti-inflammatory properties |
| Side effects |
Dry skin, lips and eyes, itching, nosebleeds, muscle aches, sensitivity to sunlight, decreased night vision, potentially severe birth defects if taken during pregnancy |
| Storage conditions |
Store at controlled room temperature (15-30В°C), protect from light |
| Substance class |
Retinoid |
| Trade name |
Accutane, Roaccutane, Claravis, others |
| Use in sports |
None |
| Water Retention |
No |
| Active ingredient, mg |
10 |
| Release form |
Tablets |
| 1 Pill, mg |
10 |
| Manufacturer |
Driada Medical |
| Packing |
Packaging (100 tablets) |
